Tested on QNAP QTS 5.0.1 with Python 2.7.13.

#!/usr/local/bin/python

import re, sys, struct, socket

def wake(mac_string):
  # Convert mac address string
  mac_segments = mac_string.split(':')
  mac_int = struct.pack('BBBBBB',
    int(mac_segments[0], 16),
    int(mac_segments[1], 16),
    int(mac_segments[2], 16),
    int(mac_segments[3], 16),
    int(mac_segments[4], 16),
    int(mac_segments[5], 16))

  # Build magic packet
  magic_packet = '\xff' * 6 + mac_int * 16

  # Send magic packet to broadcast address on UDP port 9
  sock = socket.socket(socket.AF_INET, socket.SOCK_DGRAM)
  sock.setsockopt(socket.SOL_SOCKET, socket.SO_BROADCAST, 1)
  sock.sendto(magic_packet, ("<broadcast>", 9))
  sock.close()

# Compile mac address pattern
mac_pattern = re.compile("^[0-9a-f]{2}(:[0-9a-f]{2}){5}$", re.IGNORECASE)

# Handle input and output
if len(sys.argv) != 2:
  print "Usage: wol.py <mac_address>"
  print "Example: wol.py 00:11:22:33:44:55"
  sys.exit(1)
elif mac_pattern.match(sys.argv[1]):
  wake(sys.argv[1])
  print "wol.py: Magic packet was sent to " + sys.argv[1] + "."
else:
  print "Invalid mac address format: " + sys.argv[1]
  print "Use format 00:11:22:33:44:55"
  sys.exit(2)